Intranasal NAP (davunetide) decreases tau hyperphosphorylation and moderately improves behavioral deficits in mice overexpressing α-synuclein

Genome-wide association studies have identified strong associations between the risk of developing Parkinson's disease (PD) and polymorphisms in the genes encoding α-synuclein and the microtubule-associated protein tau. However, the contribution of tau and its phosphorylated form (p-tau) to α-s...

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Detalles Bibliográficos
Autores principales: Magen, Iddo, Ostritsky, Regina, Richter, Franziska, Zhu, Chunni, Fleming, Sheila M, Lemesre, Vincent, Stewart, Alistair J, Morimoto, Bruce H, Gozes, Illana, Chesselet, Marie-Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186425/
https://www.ncbi.nlm.nih.gov/pubmed/25505609
http://dx.doi.org/10.1002/prp2.65

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186425/
https://www.ncbi.nlm.nih.gov/pubmed/25505609
http://dx.doi.org/10.1002/prp2.65

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