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Involvement of S1P(1) receptor pathway in angiogenic effects of a novel adenosine-like nucleic acid analog COA-Cl in cultured human vascular endothelial cells

COA-Cl (2Cl-C.OXT-A) is a recently developed adenosine-like nucleic acid analog that promotes angiogenesis via the mitogen-activated protein (MAP) kinases ERK1/2. Endothelial S1P(1) receptor plays indispensable roles in developmental angiogenesis. In this study, we examined the functions of S1P(1) i...

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Detalles Bibliográficos
Autores principales: Igarashi, Junsuke, Hashimoto, Takeshi, Kubota, Yasuo, Shoji, Kazuyo, Maruyama, Tokumi, Sakakibara, Norikazu, Takuwa, Yoh, Ujihara, Yoshihiro, Katanosaka, Yuki, Mohri, Satoshi, Naruse, Keiji, Yamashita, Tetsuo, Okamoto, Ryuji, Hirano, Katsuya, Kosaka, Hiroaki, Takata, Maki, Konishi, Ryoji, Tsukamoto, Ikuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186426/
https://www.ncbi.nlm.nih.gov/pubmed/25505610
http://dx.doi.org/10.1002/prp2.68