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Differential analysis of transient increases of serum cTnI in response to handling in rats

Serum cardiac troponins are the key biomarkers of myocardial necrosis in humans and in preclinical species. The use of ultrasensitive assays for serum cardiac troponin I (cTnI) as a biomarker in safety studies is hampered by interindividual differences. In this study, we investigated the effect of h...

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Detalles Bibliográficos
Autores principales: Mikaelian, Igor, Dunn, Michael E, Mould, Diane R, Hirkaler, Gerard, Geng, Wanping, Coluccio, Denise, Nicklaus, Rosemary, Singer, Thomas, Reddy, Micaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186429/
https://www.ncbi.nlm.nih.gov/pubmed/25505566
http://dx.doi.org/10.1002/prp2.11