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Differential analysis of transient increases of serum cTnI in response to handling in rats
Serum cardiac troponins are the key biomarkers of myocardial necrosis in humans and in preclinical species. The use of ultrasensitive assays for serum cardiac troponin I (cTnI) as a biomarker in safety studies is hampered by interindividual differences. In this study, we investigated the effect of h...
Autores principales: | Mikaelian, Igor, Dunn, Michael E, Mould, Diane R, Hirkaler, Gerard, Geng, Wanping, Coluccio, Denise, Nicklaus, Rosemary, Singer, Thomas, Reddy, Micaela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186429/ https://www.ncbi.nlm.nih.gov/pubmed/25505566 http://dx.doi.org/10.1002/prp2.11 |
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