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In vitro metabolism and metabolic effects of ajulemic acid, a synthetic cannabinoid agonist

Ajulemic acid is a synthetic analog of Δ(8)-THC-11-oic acid, the terminal metabolite of Δ(8)-THC. Unlike Δ(9)-THC, the psychoactive principle of Cannabis, it shows potent anti-inflammatory action and has minimal CNS cannabimimetic activity. Its in vitro metabolism by hepatocytes from rats, dogs, cyn...

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Detalles Bibliográficos
Autores principales: Burstein, Sumner H, Tepper, Mark A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186433/
https://www.ncbi.nlm.nih.gov/pubmed/25505570
http://dx.doi.org/10.1002/prp2.17