Antagonism of human CC-chemokine receptor 4 can be achieved through three distinct binding sites on the receptor

Chemokine receptor antagonists appear to access two distinct binding sites on different members of this receptor family. One class of CCR4 antagonists has been suggested to bind to a site accessible from the cytoplasm while a second class did not bind to this site. In this report, we demonstrate tha...

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Detalles Bibliográficos
Autores principales: Slack, Robert J, Russell, Linda J, Barton, Nick P, Weston, Cathryn, Nalesso, Giovanna, Thompson, Sally-Anne, Allen, Morven, Chen, Yu Hua, Barnes, Ashley, Hodgson, Simon T, Hall, David A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186434/
https://www.ncbi.nlm.nih.gov/pubmed/25505571
http://dx.doi.org/10.1002/prp2.19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186434/
https://www.ncbi.nlm.nih.gov/pubmed/25505571
http://dx.doi.org/10.1002/prp2.19

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