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Mefloquine, an anti-malaria agent, causes reactive oxygen species-dependent cell death in mast cells via a secretory granule-mediated pathway

Mast cells are known to have a detrimental impact on a variety of pathological conditions. There is therefore an urgent need of developing strategies that limit their harmful effects. The aim of this study was to accomplish this by developing a means of inducing mast cell apoptosis. The strategy was...

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Detalles Bibliográficos
Autores principales: Paivandy, Aida, Calounova, Gabriela, Zarnegar, Behdad, Öhrvik, Helena, Melo, Fabio R, Pejler, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186446/
https://www.ncbi.nlm.nih.gov/pubmed/25505612
http://dx.doi.org/10.1002/prp2.66