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Nordihydroguaiaretic acid activates hTRPA1 and modulates behavioral responses to noxious cold in mice

Nordihydroguaiaretic acid (NDGA) is a major biologically active component of the creosote bush, Larrea tridentate, widely used in unregulated therapies. NDGA is a lipoxygenase inhibitor while a derivative, terameprocol, has been trialed as a chemotherapeutic agent. When investigating fatty acid acti...

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Detalles Bibliográficos
Autores principales: Redmond, William John, Camo, Maxime, Mitchell, Vanessa, Vaughan, Christopher Walter, Connor, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186454/
https://www.ncbi.nlm.nih.gov/pubmed/25505619
http://dx.doi.org/10.1002/prp2.79