Modulation of CYP3a expression and activity in mice models of type 1 and type 2 diabetes

CYP3A4, the most abundant cytochrome P450 enzyme in the human liver and small intestine, is responsible for the metabolism of about 50% of all marketed drugs. Numerous pathophysiological factors, such as diabetes and obesity, were shown to affect CYP3A activity. Evidences suggest that drug dispositi...

Descripción completa

Detalles Bibliográficos
Autores principales: Patoine, Dany, Petit, Michaël, Pilote, Sylvie, Picard, Frédéric, Drolet, Benoit, Simard, Chantale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186456/
https://www.ncbi.nlm.nih.gov/pubmed/25505621
http://dx.doi.org/10.1002/prp2.82

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186456/
https://www.ncbi.nlm.nih.gov/pubmed/25505621
http://dx.doi.org/10.1002/prp2.82

Ejemplares similares