Investigation of the binding and cleavage characteristics of N1 neuraminidases from avian, seasonal, and pandemic influenza viruses using saturation transfer difference nuclear magnetic resonance

OBJECTIVES: The main function of influenza neuraminidase (NA) involves enzymatic cleavage of sialic acid from the surface of host cells resulting in the release of the newly produced virions from infected cells, as well as aiding the movement of virions through sialylated mucus present in the respir...

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Detalles Bibliográficos
Autores principales: Garcia, Jean-Michel, Lai, Jimmy C C, Haselhorst, Thomas, Choy, Ka Tim, Yen, Hui-Ling, Peiris, Joseph S M, von Itzstein, Mark, Nicholls, John M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186472/
https://www.ncbi.nlm.nih.gov/pubmed/24118862
http://dx.doi.org/10.1111/irv.12184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186472/
https://www.ncbi.nlm.nih.gov/pubmed/24118862
http://dx.doi.org/10.1111/irv.12184

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