Early Carcinogenesis Involves the Establishment of Immune Privilege via Intrinsic and Extrinsic Regulation of Indoleamine 2,3-dioxygenase-1: Translational Implications in Cancer Immunotherapy

Although prolonged genetic pressure has been conjectured to be necessary for the eventual development of tumor immune evasion mechanisms, recent work is demonstrating that early genetic mutations are capable of moonlighting as both intrinsic and extrinsic modulators of the tumor immune microenvironm...

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Detalles Bibliográficos
Autores principales: Holtzhausen, Alisha, Zhao, Fei, Evans, Kathy S., Hanks, Brent A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186479/
https://www.ncbi.nlm.nih.gov/pubmed/25339948
http://dx.doi.org/10.3389/fimmu.2014.00438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186479/
https://www.ncbi.nlm.nih.gov/pubmed/25339948
http://dx.doi.org/10.3389/fimmu.2014.00438

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