PKM2 regulates Gli1 expression in hepatocellular carcinoma

Hedgehog (Hh) signaling and the pyruvate kinase isoenzyme M2 (PKM2 or M2-PK) are often involved in tumorigenesis and growth. Aberrant activation of Hh signaling is found in a variety of malignancies. In tumor cells, PKM2 determines whether glucose is used for the synthesis of cellular building block...

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Detalles Bibliográficos
Autores principales: XU, QIURAN, LIU, XIN, ZHENG, XIN, YAO, YINGMIN, LIU, QINGGUANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186579/
https://www.ncbi.nlm.nih.gov/pubmed/25289083
http://dx.doi.org/10.3892/ol.2014.2441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186579/
https://www.ncbi.nlm.nih.gov/pubmed/25289083
http://dx.doi.org/10.3892/ol.2014.2441

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