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Reversing multidrug resistance in hepatocellular carcinoma cells by inhibiting extracellular signal-regulated kinase/mitogen-activated protein kinase signaling pathway activity

The aim of the present study was to evaluate whether downregulation of extracellular signal-regulated kinase 1/2 (ERK1/2) is involved in conventional reversal methods and whether the inhibitors of the ERK signaling pathway reverse multidrug resistance (MDR) in hepatocellular carcinoma (HCC) cells. T...

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Detalles Bibliográficos
Autores principales: CHEN, SIYUAN, WANG, YALI, RUAN, WENWEN, WANG, XIAOMIN, PAN, CHAO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186630/
https://www.ncbi.nlm.nih.gov/pubmed/25295120
http://dx.doi.org/10.3892/ol.2014.2521