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Development and Characterization of a Novel Mouse Line Humanized for the Intestinal Peptide Transporter PEPT1

[Image: see text] The proton-coupled oligopeptide transporter PEPT1 (SLC15A1) is abundantly expressed in the small intestine, but not colon, of mammals and found to mediate the uptake of di/tripeptides and peptide-like drugs from the intestinal lumen. However, species differences have been observed...

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Detalles Bibliográficos
Autores principales: Hu, Yongjun, Xie, Yehua, Wang, Yuqing, Chen, Xiaomei, Smith, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186676/
https://www.ncbi.nlm.nih.gov/pubmed/25148225
http://dx.doi.org/10.1021/mp500497p