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Development and Characterization of a Novel Mouse Line Humanized for the Intestinal Peptide Transporter PEPT1
[Image: see text] The proton-coupled oligopeptide transporter PEPT1 (SLC15A1) is abundantly expressed in the small intestine, but not colon, of mammals and found to mediate the uptake of di/tripeptides and peptide-like drugs from the intestinal lumen. However, species differences have been observed...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186676/ https://www.ncbi.nlm.nih.gov/pubmed/25148225 http://dx.doi.org/10.1021/mp500497p |