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Generation and Screening of Monoclonal Antibodies for ImmunoPET Imaging of IGF1R in Prostate Cancer

[Image: see text] Insulin-like growth factor 1 receptor (IGF1R) plays an important role in proliferation, apoptosis, angiogenesis, and tumor invasion. The expression level of IGF1R is related to resistance to several targeted therapies. The goal of this study was to develop an immunoPET tracer for i...

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Detalles Bibliográficos
Autores principales: Hong, Hao, Nayak, Tapas R., Shi, Sixiang, Graves, Stephen A., Fliss, Brianne C., Barnhart, Todd E., Cai, Weibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186682/
https://www.ncbi.nlm.nih.gov/pubmed/25157758
http://dx.doi.org/10.1021/mp5003637