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The Intrinsically Disordered Regions of the Drosophila melanogaster Hox Protein Ultrabithorax Select Interacting Proteins Based on Partner Topology

Interactions between structured proteins require a complementary topology and surface chemistry to form sufficient contacts for stable binding. However, approximately one third of protein interactions are estimated to involve intrinsically disordered regions of proteins. The dynamic nature of disord...

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Detalles Bibliográficos
Autores principales: Hsiao, Hao-Ching, Gonzalez, Kim L., Catanese, Daniel J., Jordy, Kristopher E., Matthews, Kathleen S., Bondos, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186791/
https://www.ncbi.nlm.nih.gov/pubmed/25286318
http://dx.doi.org/10.1371/journal.pone.0108217