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Short Hairpin RNA Library-Based Functional Screening Identified Ribosomal Protein L31 That Modulates Prostate Cancer Cell Growth via p53 Pathway

Androgen receptor is a primary transcription factor involved in the proliferation of prostate cancer cells. Thus, hormone therapy using antiandrogens, such as bicalutamide, is a first-line treatment for the disease. Although hormone therapy initially reduces the tumor burden, many patients eventuall...

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Detalles Bibliográficos
Autores principales: Maruyama, Yojiro, Miyazaki, Toshiaki, Ikeda, Kazuhiro, Okumura, Toshiyuki, Sato, Wataru, Horie-Inoue, Kuniko, Okamoto, Koji, Takeda, Satoru, Inoue, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186824/
https://www.ncbi.nlm.nih.gov/pubmed/25285958
http://dx.doi.org/10.1371/journal.pone.0108743