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The Effect of Tensile Stress on the Conformational Free Energy Landscape of Disulfide Bonds

Disulfide bridges are no longer considered to merely stabilize protein structure, but are increasingly recognized to play a functional role in many regulatory biomolecular processes. Recent studies have uncovered that the redox activity of native disulfides depends on their C–C–S–S dihedrals, [Image...

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Detalles Bibliográficos
Autores principales: Anjukandi, Padmesh, Dopieralski, Przemyslaw, Ribas–Arino, Jordi, Marx, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186883/
https://www.ncbi.nlm.nih.gov/pubmed/25286308
http://dx.doi.org/10.1371/journal.pone.0108812