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The Effect of Tensile Stress on the Conformational Free Energy Landscape of Disulfide Bonds
Disulfide bridges are no longer considered to merely stabilize protein structure, but are increasingly recognized to play a functional role in many regulatory biomolecular processes. Recent studies have uncovered that the redox activity of native disulfides depends on their C–C–S–S dihedrals, [Image...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186883/ https://www.ncbi.nlm.nih.gov/pubmed/25286308 http://dx.doi.org/10.1371/journal.pone.0108812 |