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The Interrelationship between Promoter Strength, Gene Expression, and Growth Rate

In exponentially growing bacteria, expression of heterologous protein impedes cellular growth rates. Quantitative understanding of the relationship between expression and growth rate will advance our ability to forward engineer bacteria, important for metabolic engineering and synthetic biology appl...

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Detalles Bibliográficos
Autores principales: Bienick, Matthew S., Young, Katherine W., Klesmith, Justin R., Detwiler, Emily E., Tomek, Kyle J., Whitehead, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186888/
https://www.ncbi.nlm.nih.gov/pubmed/25286161
http://dx.doi.org/10.1371/journal.pone.0109105