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The Interrelationship between Promoter Strength, Gene Expression, and Growth Rate
In exponentially growing bacteria, expression of heterologous protein impedes cellular growth rates. Quantitative understanding of the relationship between expression and growth rate will advance our ability to forward engineer bacteria, important for metabolic engineering and synthetic biology appl...
Autores principales: | Bienick, Matthew S., Young, Katherine W., Klesmith, Justin R., Detwiler, Emily E., Tomek, Kyle J., Whitehead, Timothy A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186888/ https://www.ncbi.nlm.nih.gov/pubmed/25286161 http://dx.doi.org/10.1371/journal.pone.0109105 |
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