Cargando…

Insulitis in human type 1 diabetes: a comparison between patients and animal models

Human type 1 diabetes (T1D) is considered to be an autoimmune disease, with CD8+ T-cell-mediated cytotoxicity being directed against the insulin-producing beta cells, leading to a gradual decrease in beta cell mass and the development of chronic hyperglycemia. The histopathologically defining lesion...

Descripción completa

Detalles Bibliográficos
Autor principal:	In’t Veld, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186970/ https://www.ncbi.nlm.nih.gov/pubmed/25005747 http://dx.doi.org/10.1007/s00281-014-0438-4

Ejemplares similares

Insulitis in Type 1 Diabetes: A Sticky Problem
por: Veld, Peter In't
Publicado: (2009)

Insulitis and lymphoid structures in the islets of Langerhans of a 66-year-old patient with long-standing type 1 diabetes
por: Smeets, Silke, et al.
Publicado: (2020)

Insulitis in the pancreas of non-diabetic organ donors under age 25 years with multiple circulating autoantibodies against islet cell antigens
por: Smeets, Silke, et al.
Publicado: (2021)

Spatiotemporal Dynamics of Insulitis in Human Type 1 Diabetes
por: Wedgwood, Kyle C. A., et al.
Publicado: (2016)

Insulitis in the pathogenesis of type 1 diabetes
por: Pugliese, Alberto
Publicado: (2016)

Animal Models of Diabetic Retinopathy: Summary and Comparison
por: Lai, Angela Ka Wai, et al.
Publicado: (2013)

Development of the Nonobese Diabetic Mouse and Contribution of Animal Models for Understanding Type 1 Diabetes
por: Mullen, Yoko
Publicado: (2017)

Insulitis in Human Type 1 Diabetic Pancreas: From Stem Cell Grafting to Islet Organoids for a Successful Cell-Based Therapy
por: La Noce, Marcella, et al.
Publicado: (2022)

Sheep as a large animal model for hearing research: comparison to common laboratory animals and humans
por: Lue, Po-Yi, et al.
Publicado: (2023)

Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes
por: Campbell-Thompson, Martha, et al.
Publicado: (2016)

Pancreatic β-Cells Express the Fetal Islet Hormone Gastrin in Rodent and Human Diabetes
por: Dahan, Tehila, et al.
Publicado: (2017)

Insulitis in human diabetes: a histological evaluation of donor pancreases
por: Lundberg, Marcus, et al.
Publicado: (2016)

Normal Pregnancy-Induced Islet Beta Cell Proliferation in Mouse Models That Are Deficient in Serotonin-Signaling
por: Goyvaerts, Lotte, et al.
Publicado: (2022)

Detection of Molecular Paths Associated with Insulitis and Type 1 Diabetes in Non-Obese Diabetic Mouse
por: Lindfors, Erno, et al.
Publicado: (2009)

Animal Models of GWAS-Identified Type 2 Diabetes Genes
por: da Silva Xavier, Gabriela, et al.
Publicado: (2013)

Exposure to perfluoroundecanoic acid (PFUnDA) accelerates insulitis development in a mouse model of type 1 diabetes
por: Bodin, Johanna, et al.
Publicado: (2016)

Interactions between Sleep and Emotions in Humans and Animal Models
por: Lefter, Radu, et al.
Publicado: (2022)

A Humanized Mouse Model of Autoimmune Insulitis
por: Viehmann Milam, Ashley A., et al.
Publicado: (2014)

Contrast-enhanced ultrasound with sub-micron sized contrast agents detects insulitis in mouse models of type1 diabetes
por: Ramirez, David G., et al.
Publicado: (2020)

Comparison of mechanisms and transferability of outcomes of SGLT2 inhibition between type 1 and type 2 diabetes
por: Schnell, Oliver, et al.
Publicado: (2020)

Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3
por: Heremans, Yves, et al.
Publicado: (2002)

The Spontaneously Diabetic Torii Rat: An Animal Model of Nonobese Type 2 Diabetes with Severe Diabetic Complications
por: Sasase, Tomohiko, et al.
Publicado: (2013)

Comparison of the different animal modeling and therapy methods of premature ovarian failure in animal model
por: Dai, Fangfang, et al.
Publicado: (2023)

Spontaneous and Engineered Large Animal Models of Neurofibromatosis Type 1
por: Osum, Sara H., et al.
Publicado: (2021)

Application of Animal Models in Diabetic Cardiomyopathy
por: Lee, Wang-Soo, et al.
Publicado: (2021)

Abstract: Analysis of Clinical Outcomes, Cosmetic Results, and Patient Satisfaction Following Delayed-Immediate Breast Reconstruction
por: Long, Chao, et al.
Publicado: (2017)

Molecular Processes in Stress Urinary Incontinence: A Systematic Review of Human and Animal Studies
por: Post, Wilke M., et al.
Publicado: (2022)

Contribution of animal models to diabetes research: Its history, significance, and translation to humans
por: Yagihashi, Soroku
Publicado: (2023)

What causes type 1 diabetes? Lessons from animal models
por: Buschard, Karsten
Publicado: (2011)

Modelling Diabetic Cardiomyopathy: Using Human Stem Cell-Derived Cardiomyocytes to Complement Animal Models
por: Purnama, Ujang, et al.
Publicado: (2022)

Lessons From the KK-Ay Mouse, a Spontaneous Animal Model for the Treatment of Human Type 2 Diabetic Nephropathy
por: Tomino, Yasuhiko
Publicado: (2012)

Are animal models predictive for humans?
por: Shanks, Niall, et al.
Publicado: (2009)

Aerogel Technology for Thermal Insulation of Cryogenic Tanks—Numerical Analysis for Comparison with Traditional Insulating Materials
por: Sambucci, Matteo, et al.
Publicado: (2023)

Quantification and Three-Dimensional Imaging of the Insulitis-Induced Destruction of β-Cells in Murine Type 1 Diabetes
por: Alanentalo, Tomas, et al.
Publicado: (2010)

Hyaluronan and Hyaluronan-Binding Proteins Accumulate in Both Human Type 1 Diabetic Islets and Lymphoid Tissues and Associate With Inflammatory Cells in Insulitis
por: Bogdani, Marika, et al.
Publicado: (2014)

Band insulator to Mott insulator transition in 1T-TaS(2)
por: Wang, Y. D., et al.
Publicado: (2020)

Zebrafish as an alternative animal model in human and animal vaccination research
por: Bailone, Ricardo Lacava, et al.
Publicado: (2020)

Metal-Insulator-Semiconductor Photodetectors
por: Lin, Chu-Hsuan, et al.
Publicado: (2010)

Intrinsic magnetic topological insulators
por: Wang, Pinyuan, et al.
Publicado: (2021)

The pancreas in human type 1 diabetes
por: Rowe, Patrick A., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_i6j5v1mmuk0a6man6fh3qk3osf