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Comparison of Cortical and White Matter Traumatic Brain Injury Models Reveals Differential Effects in the Subventricular Zone and Divergent Sonic Hedgehog Signaling Pathways in Neuroblasts and Oligodendrocyte Progenitors

The regenerative capacity of the central nervous system must be optimized to promote repair following traumatic brain injury (TBI) and may differ with the site and form of damage. Sonic hedgehog (Shh) maintains neural stem cells and promotes oligodendrogenesis. We examined whether Shh signaling cont...

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Detalles Bibliográficos
Autores principales: Mierzwa, Amanda J., Sullivan, Genevieve M., Beer, Laurel A., Ahn, Sohyun, Armstrong, Regina C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187014/
https://www.ncbi.nlm.nih.gov/pubmed/25290062
http://dx.doi.org/10.1177/1759091414551782