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Reversibly locked thionucleobase pairs in DNA to study base flipping enzymes
Covalently interstrand cross-linked DNA is an interesting tool to study DNA binding proteins that locally open up the DNA duplex by flipping single bases out of the DNA helix or melting whole stretches of base pairs to perform their function. The ideal DNA cross-link to study protein–DNA interaction...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187101/ https://www.ncbi.nlm.nih.gov/pubmed/25298797 http://dx.doi.org/10.3762/bjoc.10.239 |