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RNA Catalysis, Thermodynamics and the Origin of Life

The RNA World Hypothesis posits that the first self-replicating molecules were RNAs. RNA self-replicases are, in general, assumed to have employed nucleotide 5ʹ-polyphosphates (or their analogues) as substrates for RNA polymerization. The mechanism by which these substrates might be synthesized with...

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Detalles Bibliográficos
Autores principales: Scott, William G., Szöke, Abraham, Blaustein, Josh, O’Rourke, Sara M., Robertson, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187163/
https://www.ncbi.nlm.nih.gov/pubmed/25370189
http://dx.doi.org/10.3390/life4020131