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Arterial Wall Stress Controls NFAT5 Activity in Vascular Smooth Muscle Cells

BACKGROUND: Nuclear factor of activated T‐cells 5 (NFAT5) has recently been described to control the phenotype of vascular smooth muscle cells (VSMCs). Although an increase in wall stress or stretch (eg, elicited by hypertension) is a prototypic determinant of VSMC activation, the impact of this bio...

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Detalles Bibliográficos
Autores principales: Scherer, Clemens, Pfisterer, Larissa, Wagner, Andreas H., Hödebeck, Maren, Cattaruzza, Marco, Hecker, Markus, Korff, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187483/
https://www.ncbi.nlm.nih.gov/pubmed/24614757
http://dx.doi.org/10.1161/JAHA.113.000626