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Dual Modulation of the Mitochondrial Permeability Transition Pore and Redox Signaling Synergistically Promotes Cardiomyocyte Differentiation From Pluripotent Stem Cells

BACKGROUND: Cardiomyocytes that differentiate from pluripotent stem cells (PSCs) provide a crucial cellular resource for cardiac regeneration. The mechanisms of mitochondrial metabolic and redox regulation for efficient cardiomyocyte differentiation are, however, still poorly understood. Here, we sh...

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Detalles Bibliográficos
Autores principales: Cho, Sung Woo, Park, Jin‐Sung, Heo, Hye Jin, Park, Sang‐Wook, Song, Sukhyun, Kim, Injune, Han, Yong‐Mahn, Yamashita, Jun K., Youm, Jae Boum, Han, Jin, Koh, Gou Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187507/
https://www.ncbi.nlm.nih.gov/pubmed/24627421
http://dx.doi.org/10.1161/JAHA.113.000693