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CCR5 Inhibition Prevents Cardiac Dysfunction in the SIV/Macaque Model of HIV

BACKGROUND: Diastolic dysfunction is a highly prevalent cardiac abnormality in asymptomatic as well as ART‐treated human immunodeficiency virus (HIV) patients. Although the mechanisms underlying depressed cardiac function remain obscure, diastolic dysfunction in SIV‐infected rhesus macaques is highl...

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Detalles Bibliográficos
Autores principales: Kelly, Kathleen M., Tocchetti, Carlo G., Lyashkov, Alexey, Tarwater, Patrick M., Bedja, Djahida, Graham, David R., Beck, Sarah E., Metcalf Pate, Kelly A., Queen, Suzanne E., Adams, Robert J., Paolocci, Nazareno, Mankowski, Joseph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187513/
https://www.ncbi.nlm.nih.gov/pubmed/24695652
http://dx.doi.org/10.1161/JAHA.114.000874