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Reduced inhibitory gate in the barrel cortex of Neuroligin3(R451C) knock‐in mice, an animal model of autism spectrum disorders

Neuroligins are postsynaptic adhesion molecules that interacting with presynaptic neurexins ensure the cross‐talk between pre‐ and postsynaptic specializations. Rare mutations in neurexin–neuroligin genes have been linked to autism spectrum disorders (ASDs). One of these, the R451C mutation of the g...

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Detalles Bibliográficos
Autores principales: Cellot, Giada, Cherubini, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187543/
https://www.ncbi.nlm.nih.gov/pubmed/25347860
http://dx.doi.org/10.14814/phy2.12077