Cargando…

Eccentric contractions disrupt FKBP12 content in mouse skeletal muscle

Strength deficits associated with eccentric contraction‐induced muscle injury stem, in part, from impaired voltage‐gated sarcoplasmic reticulum (SR) Ca(2+) release. FKBP12 is a 12‐kD immunophilin known to bind to the SR Ca(2+) release channel (ryanodine receptor, RyR1) and plays an important role in...

Descripción completa

Detalles Bibliográficos
Autores principales: Baumann, Cory W., Rogers, Russell G., Gahlot, Nidhi, Ingalls, Christopher P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187567/
https://www.ncbi.nlm.nih.gov/pubmed/25347864
http://dx.doi.org/10.14814/phy2.12081