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Eccentric contractions disrupt FKBP12 content in mouse skeletal muscle
Strength deficits associated with eccentric contraction‐induced muscle injury stem, in part, from impaired voltage‐gated sarcoplasmic reticulum (SR) Ca(2+) release. FKBP12 is a 12‐kD immunophilin known to bind to the SR Ca(2+) release channel (ryanodine receptor, RyR1) and plays an important role in...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Periodicals, Inc.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187567/ https://www.ncbi.nlm.nih.gov/pubmed/25347864 http://dx.doi.org/10.14814/phy2.12081 |