Hypomethylation of the promoter of the catalytic subunit of protein phosphatase 2A in response to hyperglycemia

In order to identify epigenetic mechanisms through which hyperglycemia can affect gene expression durably in β cells, we screened DNA methylation changes induced by high glucose concentrations (25 mmol/L) in the BTC3 murine cell line, using an epigenome‐wide approach. Exposure of BTC3 cells to high...

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Detalles Bibliográficos
Autores principales: Tros, Fabiola, Meirhaeghe, Aline, Hadjadj, Samy, Amouyel, Philippe, Bougnères, Pierre, Fradin, Delphine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187575/
https://www.ncbi.nlm.nih.gov/pubmed/25347859
http://dx.doi.org/10.14814/phy2.12076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187575/
https://www.ncbi.nlm.nih.gov/pubmed/25347859
http://dx.doi.org/10.14814/phy2.12076

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