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Water influx into cerebrospinal fluid is significantly reduced in senile plaque bearing transgenic mice, supporting beta-amyloid clearance hypothesis of Alzheimer’s disease

Recent studies on cerebrospinal fluid (CSF) homeostasis emphasize the importance of water influx into the peri-capillary (Virchow–Robin) space through aquaporin 4 (AQP-4). This water flow is believed to have the functionality equivalent to the systemic lymphatic system and plays a critical role in b...

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Detalles Bibliográficos
Autores principales: Igarashi, Hironaka, Suzuki, Yuji, Kwee, Ingrid L, Nakada, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Maney Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188033/
https://www.ncbi.nlm.nih.gov/pubmed/25082552
http://dx.doi.org/10.1179/1743132814Y.0000000434