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Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer

Glutamine can play a critical role in cellular growth in multiple cancers. Glutamine‐addicted cancer cells are dependent on glutamine for viability, and their metabolism is reprogrammed for glutamine utilization through the tricarboxylic acid (TCA) cycle. Here, we have uncovered a missing link betwe...

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Detalles Bibliográficos
Autores principales: Yang, Lifeng, Moss, Tyler, Mangala, Lingegowda S, Marini, Juan, Zhao, Hongyun, Wahlig, Stephen, Armaiz‐Pena, Guillermo, Jiang, Dahai, Achreja, Abhinav, Win, Julia, Roopaimoole, Rajesha, Rodriguez‐Aguayo, Cristian, Mercado‐Uribe, Imelda, Lopez‐Berestein, Gabriel, Liu, Jinsong, Tsukamoto, Takashi, Sood, Anil K., Ram, Prahlad T, Nagrath, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188042/
https://www.ncbi.nlm.nih.gov/pubmed/24799285
http://dx.doi.org/10.1002/msb.20134892