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Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer
Glutamine can play a critical role in cellular growth in multiple cancers. Glutamine‐addicted cancer cells are dependent on glutamine for viability, and their metabolism is reprogrammed for glutamine utilization through the tricarboxylic acid (TCA) cycle. Here, we have uncovered a missing link betwe...
Autores principales: | Yang, Lifeng, Moss, Tyler, Mangala, Lingegowda S, Marini, Juan, Zhao, Hongyun, Wahlig, Stephen, Armaiz‐Pena, Guillermo, Jiang, Dahai, Achreja, Abhinav, Win, Julia, Roopaimoole, Rajesha, Rodriguez‐Aguayo, Cristian, Mercado‐Uribe, Imelda, Lopez‐Berestein, Gabriel, Liu, Jinsong, Tsukamoto, Takashi, Sood, Anil K., Ram, Prahlad T, Nagrath, Deepak |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188042/ https://www.ncbi.nlm.nih.gov/pubmed/24799285 http://dx.doi.org/10.1002/msb.20134892 |
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