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Identification of Amino Acid Epimerization and Isomerization in Crystallin Proteins by Tandem LC-MS
[Image: see text] Post-translational modifications that do not result in a change in mass are particularly difficult to detect by mass spectrometry. For example, isomerization of aspartic acid or epimerization of any chiral residue within a peptide do not lead to mass shifts but can be identified by...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188265/ https://www.ncbi.nlm.nih.gov/pubmed/25188914 http://dx.doi.org/10.1021/ac502296c |