Pharmacologic Blockade of JAK1/JAK2 Reduces GvHD and Preserves the Graft-Versus-Leukemia Effect

We have recently reported that interferon gamma receptor deficient (IFNγR−/−) allogeneic donor T cells result in significantly less graft-versus-host disease (GvHD) than wild-type (WT) T cells, while maintaining an anti-leukemia or graft-versus-leukemia (GvL) effect after allogeneic hematopoietic st...

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Detalles Bibliográficos
Autores principales: Choi, Jaebok, Cooper, Matthew L., Alahmari, Bader, Ritchey, Julie, Collins, Lynne, Holt, Matthew, DiPersio, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188578/
https://www.ncbi.nlm.nih.gov/pubmed/25289677
http://dx.doi.org/10.1371/journal.pone.0109799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188578/
https://www.ncbi.nlm.nih.gov/pubmed/25289677
http://dx.doi.org/10.1371/journal.pone.0109799

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