Autonomous Stimulation of Cancer Cell Plasticity by the Human NKG2D Lymphocyte Receptor Coexpressed with Its Ligands on Cancer Cells

The stimulatory NKG2D receptor on lymphocytes promotes tumor immune surveillance by targeting ligands selectively induced on cancer cells. Progressing tumors counteract by employing tactics to disable lymphocyte NKG2D. This negative dynamic is escalated as some human cancer cells co-opt expression o...

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Detalles Bibliográficos
Autores principales: Cai, Xin, Dai, Zhenpeng, Reeves, Rebecca S., Caballero-Benitez, Andrea, Duran, Kate L., Delrow, Jeffrey J., Porter, Peggy L., Spies, Thomas, Groh, Veronika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188595/
https://www.ncbi.nlm.nih.gov/pubmed/25291178
http://dx.doi.org/10.1371/journal.pone.0108942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188595/
https://www.ncbi.nlm.nih.gov/pubmed/25291178
http://dx.doi.org/10.1371/journal.pone.0108942

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