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Dynamic Epigenetic Control of Highly Conserved Noncoding Elements
BACKGROUND: Many noncoding genomic loci have remained constant over long evolutionary periods, suggesting that they are exposed to strong selective pressures. The molecular functions of these elements have been partially elucidated, but the fundamental reason for their extreme conservation is still...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188601/ https://www.ncbi.nlm.nih.gov/pubmed/25289637 http://dx.doi.org/10.1371/journal.pone.0109326 |