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Dynamic Epigenetic Control of Highly Conserved Noncoding Elements

BACKGROUND: Many noncoding genomic loci have remained constant over long evolutionary periods, suggesting that they are exposed to strong selective pressures. The molecular functions of these elements have been partially elucidated, but the fundamental reason for their extreme conservation is still...

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Detalles Bibliográficos
Autores principales: Seridi, Loqmane, Ryu, Taewoo, Ravasi, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188601/
https://www.ncbi.nlm.nih.gov/pubmed/25289637
http://dx.doi.org/10.1371/journal.pone.0109326