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Synergism between Basic Asp49 and Lys49 Phospholipase A(2) Myotoxins of Viperid Snake Venom In Vitro and In Vivo
Two subtypes of phospholipases A(2) (PLA(2)s) with the ability to induce myonecrosis, ‘Asp49’ and ‘Lys49’ myotoxins, often coexist in viperid snake venoms. Since the latter lack catalytic activity, two different mechanisms are involved in their myotoxicity. A synergism between Asp49 and Lys49 myotox...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188610/ https://www.ncbi.nlm.nih.gov/pubmed/25290688 http://dx.doi.org/10.1371/journal.pone.0109846 |