The C-Terminal Domain of Nrf1 Negatively Regulates the Full-Length CNC-bZIP Factor and Its Shorter Isoform LCR-F1/Nrf1β; Both Are Also Inhibited by the Small Dominant-Negative Nrf1γ/δ Isoforms that Down-Regulate ARE-Battery Gene Expression

The C-terminal domain (CTD, aa 686–741) of nuclear factor-erythroid 2 p45-related factor 1 (Nrf1) shares 53% amino acid sequence identity with the equivalent Neh3 domain of Nrf2, a homologous transcription factor. The Neh3 positively regulates Nrf2, but whether the Neh3-like (Neh3L) CTD of Nrf1 has...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yiguo, Qiu, Lu, Li, Shaojun, Xiang, Yuancai, Chen, Jiayu, Ren, Yonggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188613/
https://www.ncbi.nlm.nih.gov/pubmed/25290918
http://dx.doi.org/10.1371/journal.pone.0109159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188613/
https://www.ncbi.nlm.nih.gov/pubmed/25290918
http://dx.doi.org/10.1371/journal.pone.0109159

Ejemplares similares