Redox State of Pentraxin 3 as a Novel Biomarker for Resolution of Inflammation and Survival in Sepsis

In an endotoxaemic mouse model of sepsis, a tissue-based proteomics approach for biomarker discovery identified long pentraxin 3 (PTX3) as the lead candidate for inflamed myocardium. When the redox-sensitive oligomerization state of PTX3 was further investigated, PTX3 accumulated as an octamer as a...

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Detalles Bibliográficos
Autores principales: Cuello, Friederike, Shankar-Hari, Manu, Mayr, Ursula, Yin, Xiaoke, Marshall, Melanie, Suna, Gonca, Willeit, Peter, Langley, Sarah R., Jayawardhana, Tamani, Zeller, Tanja, Terblanche, Marius, Shah, Ajay M., Mayr, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188985/
https://www.ncbi.nlm.nih.gov/pubmed/24958171
http://dx.doi.org/10.1074/mcp.M114.039446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188985/
https://www.ncbi.nlm.nih.gov/pubmed/24958171
http://dx.doi.org/10.1074/mcp.M114.039446

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