Low-Frequency NNRTI-Resistant HIV-1 Variants and Relationship to Mutational Load in Antiretroviral-Naïve Subjects

Low-frequency HIV variants possessing resistance mutations against non‑nucleoside reverse transcriptase inhibitors (NNRTI), especially at HIV reverse transcriptase (RT) amino acid (aa) positions K103 and Y181, have been shown to adversely affect treatment response. Therapeutic failure correlates wit...

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Detalles Bibliográficos
Autores principales: Gupta, Shaili, Lataillade, Max, Kyriakides, Tassos C., Chiarella, Jennifer, St. John, Elizabeth P., Webb, Suzin, Moreno, Elizabeth A., Simen, Birgitte B., Kozal, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189030/
https://www.ncbi.nlm.nih.gov/pubmed/25256391
http://dx.doi.org/10.3390/v6093428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189030/
https://www.ncbi.nlm.nih.gov/pubmed/25256391
http://dx.doi.org/10.3390/v6093428

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