Fitness Impaired Drug Resistant HIV-1 Is Not Compromised in Cell-to-Cell Transmission or Establishment of and Reactivation from Latency

Both the presence of latently infected cells and cell-to-cell viral transmission are means whereby HIV can partially evade the inhibitory activities of antiretroviral drugs. The clinical use of a novel integrase inhibitor, dolutegravir (DTG), has established hope that this compound may limit HIV per...

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Detalles Bibliográficos
Autores principales: Bastarache, Sophie M., Mesplède, Thibault, Donahue, Daniel A., Sloan, Richard D., Wainberg, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189035/
https://www.ncbi.nlm.nih.gov/pubmed/25243372
http://dx.doi.org/10.3390/v6093487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189035/
https://www.ncbi.nlm.nih.gov/pubmed/25243372
http://dx.doi.org/10.3390/v6093487

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