In vivo P-glycoprotein function before and after epilepsy surgery

OBJECTIVES: To study the functional activity of the multidrug efflux transporter P-glycoprotein (Pgp) at the blood-brain barrier of patients with temporal lobe epilepsy using (R)-[(11)C]verapamil (VPM)-PET before and after temporal lobe surgery to assess whether postoperative changes in seizure freq...

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Detalles Bibliográficos
Autores principales: Bauer, Martin, Karch, Rudolf, Zeitlinger, Markus, Liu, Joan, Koepp, Matthias J., Asselin, Marie-Claude, Sisodiya, Sanjay M., Hainfellner, Johannes A., Wadsak, Wolfgang, Mitterhauser, Markus, Müller, Markus, Pataraia, Ekaterina, Langer, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189097/
https://www.ncbi.nlm.nih.gov/pubmed/25186858
http://dx.doi.org/10.1212/WNL.0000000000000858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189097/
https://www.ncbi.nlm.nih.gov/pubmed/25186858
http://dx.doi.org/10.1212/WNL.0000000000000858

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