Identification of natural inhibitors against angiotensin I converting enzyme for cardiac safety using induced fit docking and MM-GBSA studies

BACKGROUND: Cleistanthins A and B are isolated compounds from the leaves of Cleistanthus collinus Roxb (Euphorbiaceae). This plant is poisonous in nature which causes cardiovascular abnormalities such as hypotension, nonspecific ST-T changes and QTc prolongation. The biological activity predictions...

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Detalles Bibliográficos
Autores principales: Vijayakumar, Balakrishnan, Parasuraman, Subramani, Raveendran, Ramasamy, Velmurugan, Devadasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189283/
https://www.ncbi.nlm.nih.gov/pubmed/25298685
http://dx.doi.org/10.4103/0973-1296.139809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189283/
https://www.ncbi.nlm.nih.gov/pubmed/25298685
http://dx.doi.org/10.4103/0973-1296.139809

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