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Induction of Oligodendrocyte Differentiation and In Vitro Myelination by Inhibition of Rho-Associated Kinase

In inflammatory demyelinating diseases such as multiple sclerosis (MS), myelin degradation results in loss of axonal function and eventual axonal degeneration. Differentiation of resident oligodendrocyte precursor cells (OPCs) leading to remyelination of denuded axons occurs regularly in early stage...

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Detalles Bibliográficos
Autores principales: Pedraza, Carlos E., Taylor, Christopher, Pereira, Albertina, Seng, Michelle, Tham, Chui-Se, Izrael, Michal, Webb, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189421/
https://www.ncbi.nlm.nih.gov/pubmed/25289646
http://dx.doi.org/10.1177/1759091414538134