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Induction of Oligodendrocyte Differentiation and In Vitro Myelination by Inhibition of Rho-Associated Kinase
In inflammatory demyelinating diseases such as multiple sclerosis (MS), myelin degradation results in loss of axonal function and eventual axonal degeneration. Differentiation of resident oligodendrocyte precursor cells (OPCs) leading to remyelination of denuded axons occurs regularly in early stage...
Autores principales: | Pedraza, Carlos E., Taylor, Christopher, Pereira, Albertina, Seng, Michelle, Tham, Chui-Se, Izrael, Michal, Webb, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189421/ https://www.ncbi.nlm.nih.gov/pubmed/25289646 http://dx.doi.org/10.1177/1759091414538134 |
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