Polysome Fractionation and Analysis of Mammalian Translatomes on a Genome-wide Scale

mRNA translation plays a central role in the regulation of gene expression and represents the most energy consuming process in mammalian cells. Accordingly, dysregulation of mRNA translation is considered to play a major role in a variety of pathological states including cancer. Ribosomes also host...

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Detalles Bibliográficos
Autores principales: Gandin, Valentina, Sikström, Kristina, Alain, Tommy, Morita, Masahiro, McLaughlan, Shannon, Larsson, Ola, Topisirovic, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2014
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189431/
https://www.ncbi.nlm.nih.gov/pubmed/24893926
http://dx.doi.org/10.3791/51455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189431/
https://www.ncbi.nlm.nih.gov/pubmed/24893926
http://dx.doi.org/10.3791/51455

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