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Polysome Fractionation and Analysis of Mammalian Translatomes on a Genome-wide Scale
mRNA translation plays a central role in the regulation of gene expression and represents the most energy consuming process in mammalian cells. Accordingly, dysregulation of mRNA translation is considered to play a major role in a variety of pathological states including cancer. Ribosomes also host...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MyJove Corporation
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189431/ https://www.ncbi.nlm.nih.gov/pubmed/24893926 http://dx.doi.org/10.3791/51455 |