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Immunohistochemical Assessment of O(6)-Methylguanine-DNA Methyltransferase (MGMT) and Its Relationship with p53 Expression in Endometrial Cancers
O(6)-Methylguanine-DNA methyltransferase (MGMT) is a DNA repair protein, the loss of MGMT expression was commonly known due to hypermethylation of CpG islands in its promoter region. Overexpression of p53 protein may be associated with downregulated MGMT expression in brain tumors. The aims of this...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Korean Society of Cancer Prevention
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189440/ https://www.ncbi.nlm.nih.gov/pubmed/25337565 http://dx.doi.org/10.15430/JCP.2013.18.4.351 |