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Recent Advances in In Vivo Genotoxicity Testing: Prediction of Carcinogenic Potential Using Comet and Micronucleus Assay in Animal Models

Genotoxic events have been known as crucial step in the initiation of cancer. To assess the risk of cancer, genotoxicity assays, including comet, micronucleus (MN), chromosomal aberration, bacterial reverse, and sister chromatid exchange assay, can be performed. Compared with in vitro genotoxicity a...

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Detalles Bibliográficos
Autores principales: Kang, Seung Hun, Kwon, Jee Young, Lee, Jong Kwon, Seo, Young Rok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Cancer Prevention 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189446/
https://www.ncbi.nlm.nih.gov/pubmed/25337557
http://dx.doi.org/10.15430/JCP.2013.18.4.277